Ribosomal protein S21



Ribosomal protein S21 (RPS21) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It is found only in eubacteria, plant chloroplasts and mammalian mitochondria. It is involved in the initiation of polypeptide synthesis. The images at the left and at the right correspond to one representative RPS21, i.e. the crystal structure of Ribosomal protein S21 from Escherichia coli (3kc4, chain U).

3D Structures of Ribosomal protein S21
Update June 2011

S21 in small ribosomal subunit
3kc4 – EcRPS21 in 30S ribosomal subunit – Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 3ofa, 3ofb, 3ofx, 3ofy, 3ofo, 3ofp, 3or9, 3ora - EcRPS21 in 30S ribosomal subunit+16S RRNA

3bbn - RPS21 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S21 in small ribosomal subunit+tRNA+mRNA
2i2p, 2i2u - EcRPS21 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

S21 in small ribosomal subunit+P-site tRNA
2wwl - EcRPS21 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S21 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
3e1a, 3e1c - EcRPS21 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S21 in small ribosomal subunit + antibiotics
2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m, 3oaq, 3oar - EcRPS21 in 30S ribosomal subunit+16S RRNA+ antibiotic

S21 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

S21 in small ribosomal subunit + elongation factor
3fih - EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3izv – EcRPS21 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

1s1h - yRPS21 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S21 in small ribosomal subunit + various proteins
3iz6 – RPS21 in 40S ribosomal subunit +RACK1+18S RRNA – wheat – Cryo-EM

3j00 – EcRPS21 in 30S ribosomal subunit + 16S RRNA + FTSQ + apolipoprotein A-I